Involved in positive regulation of glial cell proliferation; regulation of chaperone-mediated autophagy; and response to wounding. GFAP (HGNC Symbol) Synonyms: FLJ45472: Description: Glial fibrillary acidic protein (HGNC Symbol) Entrez gene summary: This gene encodes one of the major intermediate filament proteins of mature astrocytes. It is used as a marker to distinguish astrocytes from other glial cells during development. GFAP15cc, GFAP81cc, GFAP83cc, GFAP94cc, GFAP98cc, GF5 Hybridoma clones have been derived from hybridization of Sp2/0 myeloma cells with spleen cells of Balb/c mice immunized with native human GFAP (MAbs GFAP81cc, GFAP83cc, GFAP94cc and GFAP98cc, GF5) or with synthetic peptide 1 AGFKETRASERAEMME 16 corresponding to 60-75 a.a.r. of GFAP conjugated with a carrier protein (MAb GFAP15cc). Expression of GFAP in cancer tissue.
14,15 Notably, previous studies have shown that GFAP Anti-GFAP Antibody (#AFP-001) is a highly specific antibody directed against an epitope of the rat Glial fibrillary acidic protein. The antibody can be used in western blot and immunohistochemistry applications. It has been designed to recognize GFAP from rat and mouse samples. The antibody will not recognize human GFAP. Introduction. Autoimmune glial fibrillary acidic protein (GFAP) astrocytopathy (GFAP‐A) was recently reported as a spectrum of autoimmune inflammatory central nervous system (CNS) disorders distinct from infectious meningoencephalitis and idiopathic inflammatory CNS disorders, such as multiple sclerosis (MS), neuromyelitis optica spectrum disorders (NMOSDs) and anti‐myelin oligodendrocyte Glial Fibrillary Acidic Protein (GFAP) is a major protein of the nervous system and is localized in astrocytes, stem cells, Bergmann glia and non-myelinating Schwann cells.
GFAP is an intermediate filament protein and acts as an intracellular structural component of the cytoskeleton. During embryonic and fetal life, GFAP is also
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Parenkymskademarkörer: ( NFL, GFAp,Tau). Tau-protein. Neurofilament light protein (NFL). Gliafibrillärt protein (GFAp). S-100 (Csv). CXCL13
The main intermediate filament in astrocytes is glial fibrillary acid protein (GFAP). Like other intermediate filaments, GFAP interacts with other components of the cytoskeleton, adhesion molecules, intracellular chaperones, and other proteins. Autoimmune glial fibrillary acidic protein (GFAP) astrocytopathy is an autoimmune disease of the nervous system first defined in 2016. GFAP autoantibody, especially IgG that binds to GFAPα, has been reported in the cerebrospinal fluid (CSF) and serum of patients with GFAP astrocytopathy.
Does the expression of glial fibrillary acid protein (GFAP) stain in glioblastoma tissue have a prognostic impact on NRGN,
GFAP: Glial fibrillary acidic protein; GFAP, a class-III intermediate filament, is a cell- specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial …
This GFAP preparation is an excellent protein standard for such experiments.
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It was described in 2016 by researchers of the Mayo Clinic in the United States. GFAP (HGNC Symbol) Synonyms: FLJ45472: Description: Glial fibrillary acidic protein (HGNC Symbol) Chromosome: 17: Cytoband: q21.31: Chromosome location (bp) 44903161 - … Human Glial Fibrillary Acidic Protein (GFAP) Protein is a recombinant Human protein produced in E. coli using Prokaryotic expression.
Cerebrospinalvätska. Rör el. motsv. Polypropen ("polypropylen") 10 mL eller 12 mL.
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Bongcam-Rudloff, Erik, 1957- (författare); Studies on glial fibrillary acidic protein (GFAP) in human glioma cells : in vitro and in vivo / by Erik Bongcam-Rudloff Fragile histidine triad protein.
7 Jul 2016 Herein, we identified that the glial fibrillary acidic protein (GFAP), a major intermediate filament protein of mature astrocytes, is directly
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Collapse Section The GFAP gene provides instructions for making a protein called glial fibrillary acidic protein. This protein is a member of the intermediate filament family of proteins. Intermediate filaments form networks that provide support and strength to cells. The main intermediate filament in astrocytes is glial fibrillary acid protein (GFAP).